Painkillers (opioids) such as morphine, are an extremely important and effective method of treatment for many patients with severe pain conditions. However, it is associated with certain risks, such as addiction and overdose.
Overdose of Opioids
Opioid addiction and the risks of overdose are affecting people at all levels of society and of all ages, ranging from the partying adolescent, the elderly person with an injury to the middle-aged woman trying to cope with her work week. Recently, a decision was made in Sweden to allow doctors to prescribe naloxone to people at risk for an overdose.
Naloxone is the Antidote
The antidote for an opioid overdose is the active substance naloxone that blocks the opioid from interacting with the brain's receptors and can therefore prevent respiratory arrest, coma and a fatal outcome. Naloxone is very safe to use as it does not produce any harmful side effects, no intoxication effect and is completely ineffective on people who do not overdose on opioids.
Klaria is working on the development of a naloxone product that is based on the company's unique technology, a film that attaches to the oral mucosa where the drug is absorbed and goes directly into the bloodstream.